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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

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A |     Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。      讯 8月21日,江西省政府新闻办、庐山管理局、庐山市政府联合召开“做实唱响‘庐山天下悠’ 聚力改革奋进新征程”新闻发布会。

B |   会上,庐山管理局局长、庐山市人民政府市长熊杜明介绍,面向“十五五”,将依托庐山世界级文旅资源,持续做响品牌、做大流量、做优品质、做长链条,全力打造具有烟火气、人情味、文化韵、科技感、国际范的世界级旅游目的地。以此为目标,重点抓好六个方面工作。  一是深化体制机制改革,夯实“悠”的根基。

C | 坚持一体化、集团化、市场化、专业化改革协同并进,以机制创新破解发展难题。在一体化上,探索山上山下联动、山江城湖协同的全域管理模式,推进环山全域交通便捷接驳、庐山东部索道、环庐山防火通道、环鄱阳湖旅游公路等项目建设,构建山上山下联动、城市乡村一体的交通格局。在集团化上,深入开展景区资源资产违规使用专项整治,深化“三资三化”改革,持续降本增效、提升资产运营质效。在市场化上,坚持“小政府管理、大集团运营”总体架构,扎实做好庐山疗养院改革发展“后半篇文章”,推动行政“有序下山”、市场“快速上山”。在专业化上,实施旅游经营管理人才“内培外引”,加快建立景区“三标”体系建设,以专业能力提升发展能级。  二是深耕文化根脉,丰富“悠”的内涵。以《庐山风景名胜区总体规划(2026—2035)》为纲领,坚持保护优先、活态传承,让庐山的文化底蕴可感可知。建立遗产跨区域协作机制,守护好世界文化遗产的“根”与“魂”。统筹自然山水和文化禀赋,推动诗词文化、书院文化、杏林文化、茶文化等特色资源创造性转化、创新性发展。持续开展名家名刊写名山、名人名家名医上庐山等文化活动,让千年文脉绽放时代新彩。建设并开放庐山博物馆新馆,提升展陈水平和服务能级,登高壮观天地间专题展被国家文物局、中央网信办向全国重点推介,加快推进白鹿洞书院改造提升,活化利用牯岭老建筑等历史遗存,实现合理改造更新和保留历史印记有机统一。  三是做优品牌建设,擦亮“悠”的标识。创新推出“庐山悠学、庐山悠品、庐山悠宿”三大子品牌,形成“总IP引领、子品牌支撑”的品牌矩阵。“庐山悠学”依托庐山植物园、白鹿洞书院、诗词碑林、万国别墅、世界地质公园等资源,打造人文研学、自然科考、历史研修三类精品研学体系,让庐山成为“行走的课堂”。

D | “庐山悠品”汇聚云雾茶、非遗手作、诗词文创、山野美食等庐山精粹,以创意设计赋能文化IP,建好用好线下体验空间,让每一件“庐山好物”都成为流动的文化载体。“庐山悠宿”依托牯岭云端小镇、百年别墅群落,构建高端别墅、精品山居、房车营地、星空营地梯度化旅居体系,打响“来庐山·睡好觉”新名片。今年力争研学接待突破10万人次,文创收入突破5千万元,民宿床位增长50%,全力把庐山悠系列品牌培育为文旅发展核心增长极。  四是扩容业态场景,升级“悠”的体验。立足全域旅游发展理念,统筹山上山下、景区城区、日间夜间资源,以新场景创造新需求、以新供给引领新消费。

E | 优化空间布局,遵循“山上做明珠、山下串珍珠”发展思路,高标准编制景区总体规划和重点片区专项规划,聚力打造山上山下环山环湖“旅游带”,谋划落地一批引爆性文旅项目,每年建设不少于十个美学空间,实现存量提档升级、增量做优补短。丰富高标准产品供给,迭代优化牯岭正街业态布局,推进牯岭街历史街区更新改造,打造高品质特色旅游商业集聚区。

F | 大力发展夜经济、首发经济、冰雪经济、演艺经济、赛事经济,推出夜爬、夜游、夜宿、夜演等新玩法;持续举办庐山音乐节、半程马拉松、越野赛等品牌活动;下大力气做好盘活存量资产,构建“商旅文体健”融合发展业态,让老建筑焕发新活力。  五是拓宽传播渠道,放大“悠”的声量。

G | 聚焦国际化发展定位,深化“引客入庐”全球化战略,加大海外市场推介力度,持续唱响庐山最强音。借势国际平台,以庐山迎接联合国教科文组织世界地质公园再评估为契机,强化地质遗产保护,拓展国际交流合作。整合传播资源,运用主题宣传片、短视频矩阵、达人采风等多元形式,全方位、立体化推介“庐山天下悠”品牌,不断提升国际知名度、品牌影响力和核心竞争力。

H | 深耕重点市场,精准开拓港澳台、东南亚、东亚、欧美等客源市场,构建全球化营销网络,让世界听见庐山、向往庐山、记住庐山。  六是优化服务品质,提升“悠”的质感。始终坚持以游客为中心,用心用情提升服务水平,让“悠”不仅是风景,更是体验。深化“双网合一”治理,完善景区标识、指引、服务标准化体系,常态化开展“护旅执法”行动,推出全域旅游消费投诉“先赔后处”,维护公平有序的旅游环境,让游客游得安心、玩得放心。扎实开展旅游从业人员专业培训,推进五大文明促进行动,打造“近悦远来、主客共享”的友好型景区。依托大数据智慧平台,完善闭环调度管理机制,以数字化、智慧化赋能景区精准治理,让每一位到访游客都能沉浸式感受庐山的温情与魅力。

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